I am a 58 year old man, 258 pounds, and 2 heart stents. I fully understand the risk I am taking by consuming these pills and RELEASE this website and the manufacturer of these pills from any legal action. Day 1-I chose to start taking 1 tablet twice per day to start until my metabolism becomes accustomed to these pills. There is a very good mix of ingredients in these pills. So far, I have no issues. I have no appetite... thank you for that!!! I will report my progress on a weekly basis.